Sorbitol, also known as glucitol, is a sugar alcohol with a sweet taste which the human body metabolizes slowly. It can be obtained by reduction of glucose, changing the aldehyde group to a hydroxyl group. Most of this sugar is made from corn syrup, but it is also found in apples, pears, peaches, and prunes. It is converted to fructose by Sorbitol-6-phosphate 2-dehydrogenase. Glucitol is an isomer of mannitol, another sugar alcohol; the two differ only in the orientation of the hydroxyl group on carbon 2. While similar, the two sugar alcohols have very different sources in nature, melting points, and uses.
Source: Wikipedia
Sorbitol, or glucitol as it is sometimes called, is a slow-metabolizing sugar alcohol derived from fruits, corn and seaweed. It’s a sugar substitute found in foods such as frozen desserts, sugar-free chewing gum and diabetic candies. It is only about 60% as sweet as sugar, however. It is also used as a thickener and moisturizer in beauty products. Since it’s very slow to be metabolized by the body, sorbitol does not cause insulin levels to increase as much as sugar. It also doesn’t lead to tooth decay and is used in many sugar-free cough syrups. It is a popular addition to gel toothpastes as it helps add transparency. Sorbitol is added to soaps, especially transparent glycerin bar soaps. It has moisturizing qualities and may be found in lotions and moisturizing soaps. The sugar alcohol has been used in cosmetic products for close to a century and is a Generally Recognized as Safe (GRAS) product by the United States Food and Drug Administration (FDA). This sweetener can have a laxative effect, and it is not recommended for consumption by children and those with sensitive digestion symptoms or a gastro-intestinal condition such as Irritable Bowel Syndrome (IBS). Sorbitol can cause diarrhea, bloating and gas unless it’s consumed in small quantities. It may also cause abdominal pain in some cases.
Source: wiseGEEK
USP Monograph information : Click Here.
Sorbitol
USP Method for Dextrose using Benson Polymeric Column
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Detection:
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Resin Type:
2 – Sorbitol
The relative retention times are about 0.6 for Mannitol and 1.0 for Sorbitol; and the resolution, R, between Sorbitol and Mannitol is not less than 2.0.
Additional Chromatogram(s) using Benson Polymeric Columns
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Detection:
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Resin Type:
2 – DP4
3 – DP3
4 – Maltose
5 – Glucose
6 – Galactose
7 – Fructose
8 – Mannitol
9 – Sorbitol
Part No.:
Eluent:
Flow Rate:
Detection:
Temperature:
Sample Size:
Column Size:
Resin Type:
2 – Sorbitol
Part No.:
Eluent:
Flow Rate:
Detection:
Temperature:
Sample Size:
Column Size:
Resin Type:
2 – Sorbitol
Part No.:
Eluent:
Flow Rate:
Detection:
Temperature:
Sample Size:
Column Size:
Resin Type:
2 – Glucose
3 – Xylose
4 – Galactose
5 – Arabinose
6 – Xylitol
7 – Sorbitol
Part No.:
Eluent:
Flow Rate:
Detection:
Temperature:
Sample Size:
Column Size:
Resin Type:
2 – Maltitol
3 – 1,6-GPS Isomalt
4 – Mannitol
5 – Sorbitol
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